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Ole Miss was listed as a 6.5-point favorite over Louisville with a 55.5 total for the neutral-site opener in Nashville, where the forecast called for an 88-degree kickoff temperature.

Pete Golding inherits an Ole Miss offense that ranked second nationally at nearly 490 yards per game and returns quarterback Trinidad Chambliss, who threw for 3,937 yards and 22 touchdowns, plus running back Kewan Lacy after a 1,567-yard, 24-touchdown season.

Louisville's defense ranked 16th nationally at 303.1 yards allowed per game and returns five starters, led by edge rusher Clev Lubin after 8.5 sacks and 13.5 tackles for loss.

Louisville turns its offense over to Ohio State transfer Lincoln Kienholz, a career backup, but surrounds him with explosive returning backs Isaac Brown and Keyjuan Brown, who averaged 8.8 and 7.3 yards per carry last season.

Ole Miss' defense is anchored by tackle Will Echoles after five sacks and 11.5 tackles for loss, while the returning personnel described the unit as deep across positions entering its first full season under Golding as head coach.