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Don Saunders led Purdue's defensive PFF grades at 86.6 against Indiana State after a 35-yard interception return for a touchdown, three tackles and half a tackle for loss.

Purdue edge rusher Jeremy Lewis earned an 84.2 overall defensive grade and a team-high 84.5 pass-rush grade despite no recorded box-score stats, while eight of Purdue's 12 highest-graded defenders were defensive linemen.

Purdue's Mister Clark received an 80.0 defensive grade after five tackles, two tackles for loss and a sack against Indiana State.

Purdue's coverage and discipline concerns included Jaden Mangham's fourth-quarter sideline unsportsmanlike penalty and Justin Denson Jr. allowing a 45-yard touchdown pass from backup quarterback Brady Allen to Jayden Reed.